Nanobodies From a Laptop, BCRs From a Model, and a Mutation-Agnostic Bet
Three signals this month, all pointing at the same thing: antibody discovery is becoming a computational discipline first and a wet-lab one second.
// ALL.SEQUENCES
All posts
Every entry, chronologically. Hover a row — the helix lights up; an antibody binds.
Nanobodies in silico, rabbits in wet lab, and a mutation-agnostic antibody that skips the JAK2 debate
Antibody discovery is splitting into two cultures. One trusts the model. The other trusts the rabbit. Both had a good month.
VHH Humanization Is Mostly a Search Problem, Not a Grafting Problem
Everyone frames nanobody humanization as CDR grafting. It's not. It's a search problem with a brutal fitness landscape.
Data Governance in Pharma: Notes from the Pistoia Alliance Benelux Forum #5
A speaker-by-speaker recap of the European Life Science Informatics Forum Benelux #5 at GSK Wavre: data governance, FAIR, and agentic AI in drug discovery.
Untar/Unzip Multiple Files in One Command
A quick tip showing how to untar or unzip multiple archive files in one go using find and tar.
Linking Sublime as IDE
Setting up Sublime Text 3 as a default IDE with Jekyll support and Markdown editing.